CD37 Rabbit Monoclonal Antibody [Clone ID: IPO-24 (ZC37-24)]

Specifications

Product Data
Clone Name	IPO-24 (ZC37-24)
Applications	FC, IF, IHC
Reactivity	Human
Host	Rabbit
Clonality	Monoclonal
Immunogen	This antibody was raised by immunizing mice with spleen cells of a patient with hairy cell leukemia.
Specificity	This antibody recognizes CD37, which is a cell surface protein, present mostly on mature B cells and B cell malignancies. This antibody is recommended for the analysis and detection of B cells and their malignancies as CD37 is a valuable and stable marker for peripheral mature B-cells and corresponding malignancies, such as B-cell chronic lymphocytic leukemia (B-CLL), hairy cell leukemia (HCL), and all types of B-cell non-Hodgkin's lymphoma (B-NHL). Consequently, this antibody might be useful for the treatment of B cell malignancies and autoimmune and inflammatory diseases that involve B cells in their pathology. Finally, IPO-24 antibody, might be used to identify CD37 via various techniques. For instance, it was used to evaluate CD37 expression in mantle cell lymphoma samples via immunohistochemistry (Leshchenko et al., 2010).
Formulation	PBS with 0.02% Proclin 300.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles.
Gene Name	CD37 molecule
Database Link	Entrez Gene 951 Human UniProt ID P11049
Synonyms	GP52-40; MGC120234; tetraspanin-26; Tspan-26; TSPAN26
Note	This chimeric rabbit antibody was made using the variable domain sequences of the original Mouse IgG2b format, for improved compatibility with existing reagents, assays and techniques.
Reference Data

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