Il6ra Rat Monoclonal Antibody [Clone ID: D7715A7]

CAT#: TA386281

Recombinant Anti-IL-6R (Clone D7715A7)



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CNY 6,881.00


货期*
6周

规格
    • 200 ug

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Specifications

Product Data
Clone Name D7715A7
Applications Bl, FC
Reactivity Mouse
Host Rat
Clonality Monoclonal
Immunogen This antibody was raised by immunising Lewis rats with OKT4 cells.
Specificity This antibody is specific for murine IL-6R.

This antibody binds to IL-6R-positive cells, and blocks IL-6 binding (Vink et al, 1990; Coulie et al, 1990). This antibody is able to inhibit the growth of IL6-dependent plasmacytoma T1033C2 in vitro (Coulie et al, 1990). Administration of this antibody to mice prior to challenge with T1033C2 resulted in a protection rate of 60% and prolonged survival in tumour-bearing mice (Vink et al, 1990). This antibody has been used in flow cytometry to assess IL-6Ra expression (Hoge et al, 2013). When added to dendritic cells subject to CD40 activation in vitro, this antibody neutralises IL-6 and ablates the effect of CD40 activation (Grohmann et al, 2001).
Formulation PBS with 0.02% Proclin 300.
Concentration lot specific
Conjugation Unconjugated
Storage Condition Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles.
Gene Name interleukin 6 receptor, alpha
Synonyms CD126; IL-6R; Il6r
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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