Integrin alpha 4 (ITGA4) Mouse Monoclonal Antibody [Clone ID: Natalizumab]

Specifications

Product Data
Clone Name	Natalizumab
Applications	Bl, FC
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	The RAMOS cell line, a non-EBV releasing cell line, injected into mice.
Specificity	This antibody binds to the alpha 4 binds subunit of α4β1 (also known as very late antigen 4 [VLA-4] or CD49d-CD29) and α4β7 integrin This antibody binds to human integrin alpha 4 and has been used to treat Multiple Sclerosis and Crohn's Disease.
Formulation	PBS with 0.02% Proclin 300.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles.
Gene Name	integrin subunit alpha 4
Database Link	Entrez Gene 3676 Human UniProt ID P13612
Synonyms	CD49D; IA4; MGC90518; VLA-4
Note	This chimeric mouse antibody was made using the variable domain sequences of the original Human IgG4 format, for improved compatibility with existing reagents, assays and techniques.
Reference Data

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