CD299 (CLEC4M) Rabbit Monoclonal Antibody [Clone ID: 160000000]

Specifications

Product Data
Clone Name	160000000
Applications	FC, IHC
Reactivity	Human
Host	Rabbit
Clonality	Monoclonal
Immunogen	CD299
Specificity	Human CD299, which is an oligomeric type II transmembrane protein with a C-type lectin extracellular domain, the expression of which is restricted to immature DC, macrophages in the lung, and endothelial cells in the liver. It binds ICAM-3 and ICAM-7 to mediate the interaction of DC with T lymphocytes and endothelial cells in the initial stages of immune response and in the migratory behavior of DC. CD299 also binds the gp120 protein of HIV and the E2 envelope protein of HCV, thereby playing a role in viral infection.
Formulation	PBS with 0.02% Proclin 300.
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	Please store at 4°C for up to 3 months. For longer storage, aliquot and store at -20°C. Avoid freeze and thaw cycles.
Gene Name	C-type lectin domain family 4 member M
Database Link	Entrez Gene 10332 Human UniProt ID Q9H2X3
Synonyms	CD209L; CD209L1; CD299; DC-SIGN2; DC-SIGNR; DCSIGNR; HP10347; L-SIGN; LSIGN; MGC47866; MGC129964
Note	This chimeric rabbit antibody was made using the variable domain sequences of the original murine IgG1 format, for improved compatibility with existing reagents, assays and techniques.
Reference Data

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