VCAM1 Rabbit Monoclonal Antibody [Clone ID: R02-7H1]

Specifications

Product Data
Clone Name	R02-7H1
Applications	IHC, IP, WB
Recommend Dilution	WB: 1/2000 IHC: 1/20-1/500 IP: 1/20
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Monoclonal
Immunogen	A synthetic peptide of mouse VCAM1
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	Calculated MW: 81 kDa; Observed MW: 110 kDa
Gene Name	vascular cell adhesion molecule 1
Database Link	Entrez Gene 7412 Human UniProt ID P19320
Background	Swiss-Prot Acc.P19320.Important in cell-cell recognition. Appears to function in leukocyte-endothelial cell adhesion. Interacts with integrin alpha-4/beta-1 (ITGA4/ITGB1) on leukocytes, and mediates both adhesion and signal transduction. The VCAM1/ITGA4/ITGB1 interaction may play a pathophysiologic role both in immune responses and in leukocyte emigration to sites of inflammation.
Synonyms	CD106; DKFZp779G2333; INCAM-100; L1CAM; MGC99561
Reference Data

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