RAC3 Rabbit Monoclonal Antibody [Clone ID: R01-6I8]

Specifications

Product Data
Clone Name	R01-6I8
Applications	IHC, WB
Recommend Dilution	WB: 1/1000 IHC: 1/20
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Monoclonal
Immunogen	A synthetic peptide of human RAC3
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	Calculated MW: 21 kDa; Observed MW: 21 kDa
Gene Name	ras-related C3 botulinum toxin substrate 3 (rho family, small GTP binding protein Rac3)
Database Link	Entrez Gene 5881 Human UniProt ID P60763
Background	Swiss-Prot Acc.P60763.Plasma membrane-associated small GTPase which cycles between an active GTP-bound and inactive GDP-bound state. In active state binds to a variety of effector proteins to regulate cellular responses, such as cell spreading and the formation of actin-based protusions including lamellipodia and membrane ruffles. Promotes cell adhesion and spreading on fibrinogen in a CIB1 and alpha-IIb/beta3 integrin-mediated manner.
Synonyms	p21-Rac3
Reference Data

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