MAPK6 Rabbit Monoclonal Antibody [Clone ID: R04-5B8]

Specifications

Product Data
Clone Name	R04-5B8
Applications	IHC, IP, WB
Recommend Dilution	WB: 1/1000-1/5000 IHC: 1/20-1/100 IP: 1/20
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Monoclonal
Immunogen	A synthetic peptide of human MAPK6
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	Calculated MW: 83 kDa; Observed MW: 105 kDa
Gene Name	mitogen-activated protein kinase 6
Database Link	Entrez Gene 5597 Human UniProt ID Q16659
Background	Swiss-Prot Acc.Q16659.Atypical MAPK protein. Phosphorylates microtubule-associated protein 2 (MAP2) and MAPKAPK5. The precise role of the complex formed with MAPKAPK5 is still unclear, but the complex follows a complex set of phosphorylation events: upon interaction with atypical MAPKAPK5, ERK3/MAPK6 is phosphorylated at Ser-189 and then mediates phosphorylation and activation of MAPKAPK5, which in turn phosphorylates ERK3/MAPK6. May promote entry in the cell cycle .
Synonyms	DKFZp686F03189; ERK-3; ERK3; HsT17250; p97-MAPK; p97MAPK; PRKM6
Reference Data

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