LC3B (MAP1LC3B) Mouse Monoclonal Antibody [Clone ID: 8H6-6D10-3A4]
CNY 1,999.00
CNY 3,280.00
货期*
2周
规格
经常一起买 (1)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
CNY 300.00
CNY 1,430.00
Specifications
Product Data | |
Clone Name | 8H6-6D10-3A4 |
Applications | IHC |
Recommend Dilution | IHC: 1/100-200 |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Purified recombinant protein expressed in E.coli. |
Formulation | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.03% Proclin 300, pH 7.3. |
Concentration | lot specific |
Purification | Affinity Purified |
Conjugation | Unconjugated |
Storage Condition | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Predicted Protein Size | 14,16kDa |
Gene Name | microtubule associated protein 1 light chain 3 beta |
Database Link | |
Background | Swiss-Prot Acc.Q9GZQ8.Ubiquitin-like modifier involved in formation of autophagosomal vacuoles (autophagosomes). Plays a role in mitophagy which contributes to regulate mitochondrial quantity and quality by eliminating the mitochondria to a basal level to fulfill cellular energy requirements and preventing excess ROS production. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation. Promotes primary ciliogenesis by removing OFD1 from centriolar satellites via the autophagic pathway. |
Synonyms | LC3B; MAP1A/1BLC3; MAP1ALC3 |
Reference Data |
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