H2BC21 Mouse Monoclonal Antibody [Clone ID: 7E2-2A1-8D2]

Specifications

Product Data
Clone Name	7E2-2A1-8D2
Applications	IHC, WB
Recommend Dilution	WB: 1/1000-3000 IHC: 1/100-200
Reactivity	Human, Mouse, Rat
Host	Mouse
Clonality	Monoclonal
Immunogen	Synthetic Peptide of Histone H2B
Formulation	Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.03% Proclin 300, pH 7.3.
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	Observed MW (kDa):14
Gene Name	histone cluster 2, H2be
Database Link	Entrez Gene 8349 Human UniProt ID P33778
Background	Swiss-Prot Acc.P33778.Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
Synonyms	GL105; H2B; H2B-GL105; H2B.1; H2B.q; H2B/q; H2BFQ; H2BGL105; H2BQ; MGC119802; MGC119804; MGC129733; MGC129734
Reference Data

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