HAT1 Rabbit Monoclonal Antibody [Clone ID: R02-4J1]

Specifications

Product Data
Clone Name	R02-4J1
Applications	IF, IHC, IP, WB
Recommend Dilution	WB: 1/1000 IHC: 1/100 ICC/IF: 1/100 IP: 1/20
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Monoclonal
Immunogen	Recombinant protein of human KAT1
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	Calculated MW: 50 kDa; Observed MW: 45 kDa
Gene Name	histone acetyltransferase 1
Database Link	Entrez Gene 8520 Human UniProt ID O14929
Background	Swiss-Prot Acc.O14929.Acetylates soluble but not nucleosomal histone H4 at 'Lys-5' (H4K5ac) and 'Lys-12' (H4K12ac) and, to a lesser extent, acetylates histone H2A at 'Lys-5' (H2AK5ac). Has intrinsic substrate specificity that modifies lysine in recognition sequence GXGKXG. May be involved in nucleosome assembly during DNA replication and repair as part of the histone H3.1 and H3.3 complexes. May play a role in DNA repair in response to free radical damage.
Synonyms	KAT1
Reference Data

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