EWSR1 Rabbit Monoclonal Antibody [Clone ID: R09-3A7]

Specifications

Product Data
Clone Name	R09-3A7
Applications	IF, WB
Recommend Dilution	WB: 1/2000-1/10000 ICC/IF: 1/50-1/200
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Monoclonal
Immunogen	A synthetic peptide of human EWSR1
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	Calculated MW: 69 kDa; Observed MW: 85 kDa
Gene Name	EWS RNA binding protein 1
Database Link	Entrez Gene 2130 Human UniProt ID Q01844
Background	Swiss-Prot Acc.Q01844.Might normally function as a transcriptional repressor. EWS-fusion-proteins (EFPS) may play a role in the tumorigenic process. They may disturb gene expression by mimicking, or interfering with the normal function of CTD-POLII within the transcription initiation complex. They may also contribute to an aberrant activation of the fusion protein target genes.SitesFeature keyPosition(s)Description
Synonyms	bK984G1.4; EWS
Reference Data

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