ERCC1 Rabbit Monoclonal Antibody [Clone ID: R04-3G3]
CAT#: TA384186
ERCC1 Rabbit monoclonal Antibody
Size: 20 ul
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CNY 1,999.00
CNY 3,280.00
CNY 300.00
CNY 1,430.00
Specifications
Product Data | |
Clone Name | R04-3G3 |
Applications | WB |
Recommend Dilution | WB: 1/1000 |
Reactivity | Human |
Host | Rabbit |
Clonality | Monoclonal |
Immunogen | A synthetic peptide of human ERCC1 |
Formulation | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
Concentration | lot specific |
Purification | Affinity Purified |
Conjugation | Unconjugated |
Storage Condition | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Predicted Protein Size | Calculated MW: 33 kDa; Observed MW: 39 kDa |
Gene Name | ERCC excision repair 1, endonuclease non-catalytic subunit |
Database Link | |
Background | Swiss-Prot Acc.P07992.Isoform 1: Non-catalytic component of a structure-specific DNA repair endonuclease responsible for the 5'-incision during DNA repair. Responsible, in conjunction with SLX4, for the first step in the repair of interstrand cross-links (ICL). Participates in the processing of anaphase bridge-generating DNA structures, which consist in incompletely processed DNA lesions arising during S or G2 phase, and can result in cytokinesis failure. Also required for homology-directed repair (HDR) of DNA double-strand breaks, in conjunction with SLX4.RegionsFeature keyPosition(s)Description |
Synonyms | COFS4; UV20 |
Reference Data |
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