EIF5A Rabbit Monoclonal Antibody [Clone ID: R09-3F9]

Specifications

Product Data
Clone Name	R09-3F9
Applications	IHC, IP, WB
Recommend Dilution	WB: 1/2000 IHC: 1/20 IP: 1/20
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Monoclonal
Immunogen	A synthetic peptide of human eIF5A
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	Calculated MW: 17 kDa; Observed MW: 17 kDa
Gene Name	eukaryotic translation initiation factor 5A
Database Link	Entrez Gene 1984 Human UniProt ID P63241
Background	Swiss-Prot Acc.P63241.mRNA-binding protein involved in translation elongation. Has an important function at the level of mRNA turnover, probably acting downstream of decapping. Involved in actin dynamics and cell cycle progression, mRNA decay and probably in a pathway involved in stress response and maintenance of cell wall integrity. With syntenin SDCBP, functions as a regulator of p53/TP53 and p53/TP53-dependent apoptosis. Regulates also TNF-alpha-mediated apoptosis. Mediates effects of polyamines on neuronal process extension and survival. May play an important role in brain development and function, and in skeletal muscle stem cell differentiation. Also described as a cellular cofactor of human T-cell leukemia virus type I (HTLV-1) Rex protein and of human immunodeficiency virus type 1 (HIV-1) Rev protein, essential for mRNA export of retroviral transcripts.
Synonyms	eIF-4D; EIF-5A; eIF-5A-1; eIF-5A1; EIF5A1; eIF5AI; MGC99547; MGC104255
Reference Data

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