CTNND1 Rabbit Monoclonal Antibody [Clone ID: R01-4G3]

Specifications

Product Data
Clone Name	R01-4G3
Applications	IHC, IP, WB
Recommend Dilution	WB: 1/1000-1/5000 IHC: 1/20-1/100 IP: 1/20-1/50
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Monoclonal
Immunogen	A synthetic peptide of human delta 1 Catenin
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	Calculated MW: 108 kDa; Observed MW: 108 kDa
Gene Name	catenin delta 1
Database Link	Entrez Gene 1500 Human UniProt ID O60716
Background	Swiss-Prot Acc.O60716.Binds to and inhibits the transcriptional repressor ZBTB33, which may lead to activation of target genes of the Wnt signaling pathway . Associates with and regulates the cell adhesion properties of both C-, E- and N-cadherins, being critical for their surface stability. Implicated both in cell transformation by SRC and in ligand-induced receptor signaling through the EGF, PDGF, CSF-1 and ERBB2 receptors. Promotes GLIS2 C-terminal cleavage.
Synonyms	CAS; CTNND; KIAA0384; p120; p120(cas); p120(ctn); P120CAS; P120CTN
Reference Data

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