CAMK2A Rabbit Monoclonal Antibody [Clone ID: R09-9E5]
CAT#: TA383856
CaMKII alpha Rabbit monoclonal Antibody
Size: 20 ul
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Specifications
Product Data | |
Clone Name | R09-9E5 |
Applications | WB |
Recommend Dilution | WB: 1/1000-1/2000 |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Monoclonal |
Immunogen | A synthetic peptide of human CaMKII |
Formulation | 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA |
Concentration | lot specific |
Purification | Affinity Purified |
Conjugation | Unconjugated |
Storage Condition | Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles. |
Predicted Protein Size | Calculated MW: 54 kDa; Observed MW: 54 kDa |
Gene Name | calcium/calmodulin dependent protein kinase II alpha |
Database Link | |
Background | Swiss-Prot Acc.Q9UQM7.Calcium/calmodulin-dependent protein kinase that functions autonomously after Ca2+/calmodulin-binding and autophosphorylation, and is involved in synaptic plasticity, neurotransmitter release and long-term potentiation. Member of the NMDAR signaling complex in excitatory synapses, it regulates NMDAR-dependent potentiation of the AMPAR and therefore excitatory synaptic transmission . Regulates dendritic spine development (PubMed:28130356). Also regulates the migration of developing neurons (PubMed:29100089). Phosphorylates the transcription factor FOXO3 to activate its transcriptional activity (PubMed:23805378). |
Synonyms | CAMKA; CaMKIINalpha; KIAA0968 |
Reference Data |
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