BTF3 Rabbit Monoclonal Antibody [Clone ID: R01-2B7]

Specifications

Product Data
Clone Name	R01-2B7
Applications	IHC, IP, WB
Recommend Dilution	WB: 1/1000 IHC: 1/50 IP: 1/20
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Monoclonal
Immunogen	Recombinant protein of human BTF3
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	Calculated MW: 22 kDa; Observed MW: 22 kDa
Gene Name	basic transcription factor 3
Database Link	Entrez Gene 689 Human UniProt ID P20290
Background	Swiss-Prot Acc.P20290.When associated with NACA, prevents inappropriate targeting of non-secretory polypeptides to the endoplasmic reticulum (ER). Binds to nascent polypeptide chains as they emerge from the ribosome and blocks their interaction with the signal recognition particle (SRP), which normally targets nascent secretory peptides to the ER. BTF3 is also a general transcription factor that can form a stable complex with RNA polymerase II. Required for the initiation of transcription.
Synonyms	BETA-NAC; BTF3a; BTF3b; NACB
Reference Data

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