Ataxin 1 (ATXN1) Rabbit Monoclonal Antibody [Clone ID: R01-8H1]

Specifications

Product Data
Clone Name	R01-8H1
Applications	IP, WB
Recommend Dilution	WB: 1/1000 IP: 1/20
Reactivity	Mouse
Host	Rabbit
Clonality	Monoclonal
Immunogen	Recombinant protein of human Ataxin 1
Formulation	50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	Calculated MW: 87 kDa; Observed MW: 105 kDa
Gene Name	ataxin 1
Database Link	UniProt ID P54253
Background	Swiss-Prot Acc.P54253.Chromatin-binding factor that repress Notch signaling in the absence of Notch intracellular domain by acting as a CBF1 corepressor. Binds to the HEY promoter and might assist, along with NCOR2, RBPJ-mediated repression. Binds RNA in vitro. May be involved in RNA metabolism (PubMed:21475249). In concert with CIC and ATXN1L, involved in brain development .
Synonyms	ATX1; D6S504E; OTTHUMP00000016065; SCA1
Reference Data

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