RNF12 (RLIM) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB,1:500 - 1:2000
Reactivity	Human, Mouse
Modifications	Unmodified
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 535-624 of human RLIM (NP_057204.2).
Formulation	Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Concentration	lot specific
Purification	Affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20℃. Avoid freeze / thaw cycles.
Predicted Protein Size	52kDa/68kDa
Gene Name	ring finger protein, LIM domain interacting
Database Link	Entrez Gene 51132 Human UniProt ID Q9NVW2
Background	The protein encoded by this gene is a RING-H2 zinc finger protein. It has been shown to be an E3 ubiquitin protein ligase that targets LIM domain binding 1 (LDB1/CLIM), and causes proteasome-dependent degradation of LDB1. This protein and LDB1 are co-repressors of LHX1/LIM-1, a homeodomain transcription factor. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Synonyms	DKFZp686N06224; FLJ25923; FLJ41093; FLJ42887; FLJ45986; MGC15161; NY-REN-43; OTTHUMP00000023575; R-LIM; RNF12
Reference Data

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