MCL1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ICC/IF, IHC, WB
Recommend Dilution	WB,1:500 - 1:2000 IHC,1:100 - 1:200 IF,1:50 - 1:200
Reactivity	Human, Mouse
Modifications	Unmodified
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthetic peptide corresponding to a sequence within amino acids 120-220 of human MCL1 (NP_068779.1).
Formulation	Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Concentration	lot specific
Purification	Affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20℃. Avoid freeze / thaw cycles.
Predicted Protein Size	28kDa/37kDa
Gene Name	myeloid cell leukemia 1
Database Link	Entrez Gene 4170 Human UniProt ID Q07820
Background	This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing.
Synonyms	Bcl2-L-3; BCL2L3; EAT; Mcl-1; mcl1/EAT; MCL1L; MCL1S; MGC1839; MGC104264; TM
Reference Data

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