H2BC21 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ChIP, ICC/IF, IHC, WB
Recommend Dilution	WB,1:500 - 1:2000 IHC,1:50 - 1:200 IF,1:50 - 1:200 ChIP,1:50 - 1:200
Reactivity	Human, Mouse, Rat, Other (Wide Range)
Modifications	Acetyl K12
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthetic acetylated peptide around K12 of human Histone H2B (NP_003519.1).
Formulation	Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Concentration	lot specific
Purification	Affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20℃. Avoid freeze / thaw cycles.
Predicted Protein Size	13kDa
Gene Name	histone cluster 2, H2be
Database Link	Entrez Gene 8349 Human UniProt ID Q16778
Background	Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-dependent histone that is a member of the histone H2B family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. The protein has antibacterial and antifungal antimicrobial activity.
Synonyms	GL105; H2B; H2B-GL105; H2B.1; H2B.q; H2B/q; H2BFQ; H2BGL105; H2BQ; MGC119802; MGC119804; MGC129733; MGC129734
Reference Data

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