DUSP9 Rabbit Polyclonal Antibody

CAT#: TA375660

DUSP9 Rabbit polyclonal Antibody



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CNY 2,900.00


货期*
2周

规格
    • 100 ul

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beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
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Specifications

Product Data
Applications ICC/IF, WB
Recommend Dilution WB,1:200 - 1:2000
IHC,1:20 - 1:200
IF,1:20 - 1:100
Reactivity Human, Mouse
Modifications Unmodified
Host Rabbit
Clonality Polyclonal
Immunogen Recombinant protein of human DUSP9
Formulation Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Concentration lot specific
Purification Affinity purification
Conjugation Unconjugated
Storage Condition Store at -20℃. Avoid freeze / thaw cycles.
Predicted Protein Size 41kDa
Gene Name dual specificity phosphatase 9
Background The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which is associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product shows selectivity for members of the ERK family of MAP kinases and is localized to the cytoplasm and nucleus. Aberrant expression of this gene is associated with type 2 diabetes and cancer progression in several cell types. Alternate splicing results in multiple transcript variants.
Synonyms MKP-4; MKP4; OTTHUMP00000025953
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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