CLSTN1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB,1:200 - 1:2000 IF,1:50 - 1:200
Reactivity	Mouse, Rat
Modifications	Unmodified
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 29-350 of human CLSTN1 (NP_055759.3).
Formulation	Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Concentration	lot specific
Purification	Affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20℃. Avoid freeze / thaw cycles.
Predicted Protein Size	108kDa/109kDa
Gene Name	calsyntenin 1
Database Link	UniProt ID O94985
Background	This gene is a member of the calsyntenin family, a subset of the cadherin superfamily. The encoded transmembrane protein, also known as alcadein-alpha, is thought to bind to kinesin-1 motors to mediate the axonal anterograde transport of certain types of vesicle. Amyloid precursor protein (APP) is trafficked via these vesicles and so this protein is being investigated to see how it might contribute to the mechanisms underlying Alzheimer's disease. Alternative splicing results in multiple transcript variants.
Synonyms	ALC-ALPHA; Alcadein-alpha; alcalpha1; alcalpha2; CS1; CSTN1; FLJ32258; KIAA0911; PIK3CD; XB31alpha
Reference Data

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