CDK9 Rabbit Polyclonal Antibody
CAT#: TA374576
Phospho-CDK9-T186 Rabbit polyclonal Antibody
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CNY 2,900.00
货期*
2周
规格
经常一起买 (1)
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Specifications
Product Data | |
Applications | WB |
Recommend Dilution | WB,1:500 - 1:2000 |
Reactivity | Human, Mouse, Rat |
Modifications | Phospho T186 |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | A synthetic phosphorylated peptide around T186 of human CDK9 (NP_001252.1). |
Formulation | Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |
Concentration | lot specific |
Purification | Affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20℃. Avoid freeze / thaw cycles. |
Predicted Protein Size | 42kDa/53kDa |
Gene Name | cyclin-dependent kinase 9 |
Database Link | |
Background | The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS. |
Synonyms | C-2k; CDC2L4; CTK1; PITALRE; TAK |
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