KDM5B Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB: 200-1000 WB positive control: Human placenta tissue lysate
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide of human KDM5B
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C.
Predicted Protein Size	176 kDa
Gene Name	lysine demethylase 5B
Database Link	Entrez Gene 10765 Human UniProt ID Q9UGL1
Background	This gene encodes a lysine-specific histone demethylase that belongs to the jumonji/ARID domain-containing family of histone demethylases. The encoded protein is capable of demethylating tri-, di- and monomethylated lysine 4 of histone H3. This protein plays a role in the transcriptional repression or certain tumor suppressor genes and is upregulated in certain cancer cells. This protein may also play a role in genome stability and DNA repair. Alternate splicing results in multiple transcript variants.
Synonyms	CT31; FLJ10538; FLJ12459; FLJ12491; FLJ16281; FLJ23670; JARID1B; PLU-1; PLU1; PUT1; RBBP2H1; RBBP2H1A; RBP2-H1; RBP2-like
Reference Data

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