CHFR Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 200-1000 WB positive control: Hela,Jurkat,A549,HepG2,293T and 231 cell lysates IHC: 20-100 Positive control: Human ovarian cancer Predicted cell location: Nucleus
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide of human CHFR
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C.
Predicted Protein Size	73 kDa
Gene Name	checkpoint with forkhead and ring finger domains, E3 ubiquitin protein ligase
Database Link	Entrez Gene 55743 Human UniProt ID Q96EP1
Background	This gene encodes an E3 ubiquitin-protein ligase required for the maintenance of the antephase checkpoint that regulates cell cycle entry into mitosis and, therefore, may play a key role in cell cycle progression and tumorigenesis. The encoded protein has an N-terminal forkhead-associated domain, a central RING-finger domain, and a cysteine-rich C-terminal region. Alternatively spliced transcript variants that encode different protein isoforms have been described.
Synonyms	FLJ10796; FLJ33629; RNF116; RNF196
Reference Data

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