BCS1L Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 150-300 Positive control: Human colorectal cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein of human BCS1L
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C.
Gene Name	BCS1 homolog, ubiquinol-cytochrome c reductase complex chaperone
Database Link	Entrez Gene 617 Human UniProt ID Q9Y276
Background	This gene encodes a homolog of the S. cerevisiae bcs1 protein which is involved in the assembly of complex III of the mitochondrial respiratory chain. The encoded protein does not contain a mitochondrial targeting sequence but experimental studies confirm that it is imported into mitochondria. Mutations in this gene are associated with mitochondrial complex III deficiency and the GRACILE syndrome. Several alternatively spliced transcripts encoding two different isoforms have been described.
Synonyms	BCS; BCS1; BCS1-like; BJS; FLNMS; GRACILE; h-BCS; H-BCS1; OTTHUMP00000164147; OTTHUMP00000206494; OTTHUMP00000206495; OTTHUMP00000206496; PTD
Reference Data

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