THOC3 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 1000-5000 WB positive control: Jurkat and PC3 cell lysates IHC: 50-200 Positive control: Human esophagus cancer Predicted cell location: Cytoplasm and Nucleus
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein of human THOC3
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C.
Predicted Protein Size	39 kDa
Gene Name	THO complex 3
Database Link	Entrez Gene 84321 Human UniProt ID Q96J01
Background	This gene encodes a component of the nuclear THO transcription elongation complex, which is part of the larger transcription export (TREX) complex that couples messenger RNA processing and export. In humans, the transcription export complex is recruited to the 5'-end of messenger RNAs in a splicing- and cap-dependent manner. Studies of a related complex in mouse suggest that the metazoan transcription export complex is involved in cell differentiation and development. A pseudogene of this gene has been defined on chromosome 5.
Synonyms	hTREX45; MGC5469; TEX1; Tho3
Reference Data

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