EIF4A2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: Mouse brain tissue, K562 and Raji cell lysates IHC: 50-200 Positive control: Human gastric cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein of human EIF4A2
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C.
Predicted Protein Size	46 kDa
Gene Name	eukaryotic translation initiation factor 4A2
Database Link	Entrez Gene 1974 Human UniProt ID Q14240
Background	ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5'-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.
Synonyms	BM-010; DDX2B; eIF-4A-II; EIF4A; eIF4A-II; EIF4F
Reference Data

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