CBARA1 (MICU1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 200-1000 WB positive control: HUVEC cell lysate IHC: 25-100 Positive control: Human thyroid cancer Predicted cell location: Cytoplasm and Nucleus
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein of human MICU1
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C.
Predicted Protein Size	54 kDa
Gene Name	mitochondrial calcium uptake 1
Database Link	Entrez Gene 10367 Human UniProt ID Q9BPX6
Background	This gene encodes an essential regulator of mitochondrial Ca2+ uptake under basal conditions. The encoded protein interacts with the mitochondrial calcium uniporter, a mitochondrial inner membrane Ca2+ channel, and is essential in preventing mitochondrial Ca2+ overload, which can cause excessive production of reactive oxygen species and cell stress. Alternatively spliced transcript variants encoding different isoforms have been described.
Synonyms	C730016L05Rik; Calc; Cbara1
Reference Data

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