GCNT2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC
Recommend Dilution	IHC: 40-200 Positive control: Human colorectal cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Fusion protein of human GCNT2
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C.
Gene Name	glucosaminyl (N-acetyl) transferase 2, I-branching enzyme (I blood group)
Database Link	Entrez Gene 2651 Human UniProt ID Q8N0V5
Background	This gene encodes the enzyme responsible for formation of the blood group I antigen. The i and I antigens are distinguished by linear and branched poly-N-acetyllactosaminoglycans, respectively. The encoded protein is the I-branching enzyme, a beta-1,6-N-acetylglucosaminyltransferase responsible for the conversion of fetal i antigen to adult I antigen in erythrocytes during embryonic development. Mutations in this gene have been associated with adult i blood group phenotype. Alternatively spliced transcript variants encoding different isoforms have been described.
Synonyms	bA360O19.2; bA421M1.1; CCAT; GCNT2C; GCNT5; IGNT; II; MGC163396; N-acetylglucosaminyltransferase; NACGT1; NAGCT1; ULG3
Reference Data

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