LIMS1 Rabbit Polyclonal Antibody
CAT#: TA369192S
LIMS1 rabbit polyclonal antibody
Size: 100 ul
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CNY 800.00
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Specifications
Product Data | |
Applications | IHC, WB |
Recommend Dilution | WB: 200-1000 WB positive control: Mouse lung tissue IHC: 25-100 Positive control: Human colon cancer Predicted cell location: Cytoplasm |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Fusion protein of human LIMS1 |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C. |
Predicted Protein Size | 37 kDa |
Gene Name | LIM zinc finger domain containing 1 |
Database Link | |
Background | The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene. |
Synonyms | OTTHUMP00000161608; PINCH; PINCH-1; PINCH1 |
Reference Data |
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