JIP3 (MAPK8IP3) Rabbit Polyclonal Antibody
CAT#: TA368581S
MAPK8IP3 rabbit polyclonal antibody
Size: 100 ul
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CNY 800.00
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CNY 1,430.00
Specifications
Product Data | |
Applications | IHC |
Recommend Dilution | IHC: 40-200 Positive control: Human tonsil Predicted cell location: Cytoplasm |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human MAPK8IP3 |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C. |
Gene Name | mitogen-activated protein kinase 8 interacting protein 3 |
Database Link | |
Background | The protein encoded by this gene shares similarity with the product of Drosophila syd gene, required for the functional interaction of kinesin I with axonal cargo. Studies of the similar gene in mouse suggested that this protein may interact with, and regulate the activity of numerous protein kinases of the JNK signaling pathway, and thus function as a scaffold protein in neuronal cells. The C. elegans counterpart of this gene is found to regulate synaptic vesicle transport possibly by integrating JNK signaling and kinesin-1 transport. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. |
Synonyms | DKFZp762N1113; FLJ00027; JIP-3; JIP3; JSAP1; KIAA1066; syd; SYD2 |
Reference Data |
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