FKBP51 (FKBP5) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 500-2000 WB positive control: A172, Hela, HepG2, K562 and PC3 cell lysates IHC: 50-300 Positive control: Human ovarian cancer Predicted cell location: Nucleus
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide of human FKBP5
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C.
Predicted Protein Size	51 kDa
Gene Name	FK506 binding protein 5
Database Link	Entrez Gene 2289 Human UniProt ID Q13451
Background	The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds to the immunosuppressants FK506 and rapamycin. It is thought to mediate calcineurin inhibition. It also interacts functionally with mature hetero-oligomeric progesterone receptor complexes along with the 90 kDa heat shock protein and P23 protein. This gene has been found to have multiple polyadenylation sites. Alternative splicing results in multiple transcript variants.
Synonyms	AIG6; FKBP-51; FKBP51; FKBP54; MGC111006; OTTHUMP00000016268; P54; PPIase; Ptg-10; rotamase
Reference Data

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