DUSP2 Rabbit Polyclonal Antibody
CAT#: TA367040
DUSP2 rabbit polyclonal antibody
Size: 25 ul
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CNY 1,999.00
CNY 3,280.00
CNY 300.00
CNY 1,430.00
Specifications
Product Data | |
Applications | WB |
Recommend Dilution | WB: 500-2000 WB positive control: Mouse thymus tissue, Mouse liver tissue lysates |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Synthetic peptide of human DUSP2 |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C. |
Predicted Protein Size | 34 kDa |
Gene Name | dual specificity phosphatase 2 |
Database Link | |
Background | The protein encoded by this gene is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphotyrosine residues. They negatively regulate members of the mitogen-activated protein (MAP) kinase superfamily (MAPK/ERK, SAPK/JNK, p38), which are associated with cellular proliferation and differentiation. Different members of the family of dual specificity phosphatases show distinct substrate specificities for various MAP kinases, different tissue distribution and subcellular localization, and different modes of inducibility of their expression by extracellular stimuli. This gene product inactivates ERK1 and ERK2, is predominantly expressed in hematopoietic tissues, and is localized in the nucleus. |
Synonyms | PAC-1; PAC1 |
Reference Data |
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