ASPP1 (PPP1R13B) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 200-1000 WB positive control: HepG2 cell IHC: 10-50 Positive control: Human prostate cancer Predicted cell location: Cytoplasm and Nucleus
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide of human PPP1R13B
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C.
Predicted Protein Size	120 kDa
Gene Name	protein phosphatase 1 regulatory subunit 13B
Database Link	Entrez Gene 23368 Human UniProt ID Q96KQ4
Background	This gene encodes a member of the ASPP (apoptosis-stimulating protein of p53) family of p53 interacting proteins. The protein contains four ankyrin repeats and an SH3 domain involved in protein-protein interactions. ASPP proteins are required for the induction of apoptosis by p53-family proteins. They promote DNA binding and transactivation of p53-family proteins on the promoters of proapoptotic genes. Expression of this gene is regulated by the E2F transcription factor.
Synonyms	ASPP1; KIAA0771; p53BP2-like; p85
Reference Data

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