ERK1 (MAPK3) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 1000-5000 WB positive control: A375, Hela, 293T, LOVO, 231 cell lysates IHC: 50-100 Positive control: Human liver cancer Predicted cell location: Cytoplasm
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide of human MAPK3
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C.
Predicted Protein Size	43 kDa
Gene Name	mitogen-activated protein kinase 3
Database Link	Entrez Gene 5595 Human UniProt ID P27361
Background	The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described.
Synonyms	ERK-1; ERK1; ERT2; HS44KDAP; HUMKER1A; MGC20180; OTTHUMP00000174538; p44-ERK1; p44-MAPK; P44ERK1; p44mapk; PRKM3
Reference Data

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