ITM2C Rabbit Polyclonal Antibody
CAT#: TA366434
ITM2C rabbit polyclonal antibody
Size: 25 ul
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CNY 1,999.00
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CNY 1,430.00
Specifications
Product Data | |
Applications | WB |
Recommend Dilution | WB: 500-2000 WB positive control: HepG2 cell, Mouse brain tissue lysates |
Reactivity | Human, Mouse |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Fusion protein of human ITM2C |
Formulation | pH7.4 PBS, 0.05% NaN3, 40% Glycerol |
Concentration | lot specific |
Purification | Antigen affinity purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C. |
Predicted Protein Size | 30 kDa |
Gene Name | integral membrane protein 2C |
Database Link | |
Background | Negative regulator of amyloid-beta peptide production. May inhibit the processing of APP by blocking its access to alpha- and beta-secretase. Binding to the beta-secretase-cleaved APP C-terminal fragment is negligible, suggesting that ITM2C is a poor gamma-secretase cleavage inhibitor. May play a role in TNF-induced cell death and neuronal differentiation. |
Synonyms | BRI3; BRICD2C; E25; E25C; hRPC.1050_D_4; ITM3 |
Reference Data |
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