DNA polymerase eta (POLH) Rabbit Polyclonal Antibody

CAT#: TA366018

POLH rabbit polyclonal antibody

Size: 25 ul 100 ul



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TA366018 is a possible alternative to TA322495.

CNY 1,999.00

CNY 3,280.00


货期*
2周

规格
    • 100 ul

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Specifications

Product Data
Applications IHC, WB
Recommend Dilution WB: 500-2000
WB positive control: A172, 231, Jurkat, HepG2 and Hela cell lysates
IHC: 50-300
Positive control: Human tonsil
Predicted cell location: Nucleus
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Immunogen Fusion protein of human POLH
Formulation pH7.4 PBS, 0.05% NaN3, 40% Glycerol
Concentration lot specific
Purification Antigen affinity purification
Conjugation Unconjugated
Storage Condition Store at -20°C.
Predicted Protein Size 78 kDa
Gene Name polymerase (DNA) eta
Background This gene encodes a member of the Y family of specialized DNA polymerases. It copies undamaged DNA with a lower fidelity than other DNA-directed polymerases. However, it accurately replicates UV-damaged DNA; when thymine dimers are present, this polymerase inserts the complementary nucleotides in the newly synthesized DNA, thereby bypassing the lesion and suppressing the mutagenic effect of UV-induced DNA damage. This polymerase is thought to be involved in hypermutation during immunoglobulin class switch recombination. Mutations in this gene result in XPV, a variant type of xeroderma pigmentosum. Several transcript variants encoding different isoforms have been found for this gene.
Synonyms FLJ16395; FLJ21978; RAD30; RAD30A; XP-V; XPV
Reference Data
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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