Nucleobindin 2 (NUCB2) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA
Recommend Dilution	This antibody has been tested and validated in ELISA against Nesfatin-1 (24-38). Other applications like immunohistochemistry (IHC), FACS or Western Blot may work as well. Optimal dilutions should be determined by the end user.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Formulation	Neat undiluted antiserum, lyophilized, packaged under nitrogen. Reconstitute by adding 50µl distilled water. This will give the equivalent of undiluted antiserum.
Concentration	N/A
Conjugation	Unconjugated
Storage Condition	Original vial: at least one year at 4° - 8°C from date of delivery. Minimize repeated thawing and freezing of the antiserum by freezing aliquots at -20°C or below.
Gene Name	nucleobindin 2
Database Link	Entrez Gene 4925 Human UniProt ID P80303
Background	Nesfatin-1 is a metabolic polypeptide encoded in the N-terminal region of the precursor protein, Nucleobindin-2 (NUCB2). Recombinant human Nesfatin-1 is a 9.7 kDa protein containing 82 amino acid residues. It participates in the regulation of hunger and fat storage. Increased nesfatin-1 in the hypothalamus contributes to diminished hunger and a potential loss of body fat and weight. Nesfatin-1 is originally identified as a hypothalamic neuropeptide, but it is also expressed in other areas of the brain, and in pancreatic islets β-cells, gastric endocrine cells and adipocytes. This antibody was generated by immunization of rabbits with Nesfatin-1 (24-38) coupled to a carrier protein.
Synonyms	NEFA
Reference Data

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