Chromogranin A (CHGA) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA
Recommend Dilution	This antibody has been tested and validated in ELISA against Pancreastatin (33-48) / Chromogranin A (240-301). Other applications like immunohistochemistry (IHC), FACS or Western Blot may work as well. Optimal dilutions should be determined by the end user.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide H-Glu-Glu-Glu-Glu-Glu-Met-Ala-Val-Val-Pro-Gln-Gly- Leu-Phe-Arg-Gly-NH2 coupled to carrier protein.
Formulation	Diluted antiserum, lyophilized, packaged under nitrogen. Reconstitute by adding 50µl distilled water. This will give the equivalent of undiluted antiserum.
Concentration	N/A
Conjugation	Unconjugated
Storage Condition	Original vial: at least one year at 4° - 8°C from date of delivery. Minimize repeated thawing and freezing of the antiserum by freezing aliquots at -20°C or below.
Gene Name	chromogranin A
Database Link	Entrez Gene 1113 Human UniProt ID P10645
Background	Pancreastatin is a 49 amino acid peptide found in many cells of the neuroendocrine system. It is produced from the proteolytic cleavage of its precursor, Chromogranin A [Chromogranin A (240-288)]. It is localized to insulin-containing beta cells, glucagon- containing alpha cells, and somatostatin-containing D cells of the pancreatic islet. Pancreastatin inhibits release of somatostatin upon glucose stimulation and it may also control carbohydrate metabolism and hyperglycemia. This antibody was generated by immunization of rabbits with Pancreastatin (33-48) / Chromogranin-A (286-301)coupled to a carrier protein.
Synonyms	CgA; SP-I
Reference Data

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