Adrenomedullin (ADM) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	ELISA
Recommend Dilution	This antibody has been tested and validated in ELISA against Adrenomedullin. Other applications like immunohistochemistry (IHC), FACS or Western Blot may work as well. Optimal dilutions should be determined by the end user.
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide H-Tyr-Arg-Gln-Ser-Met-Asn-Asn-Phe-Gln-Gly-Leu- Arg-Ser-Phe-Gly-Cys-Arg-Phe-Gly-Thr-Cys-Thr-Val-Gln-Lys-Leu-Ala- His-Gln-Ile-Tyr-Gln-Phe-Thr-Asp-Lys-Asp-Lys-Asp-Asn-Val-Ala-Pro-Arg- Ser-Lys-Ile-Ser-Pro-Gln-Gly-Tyr-NH2, (Disulfide bond) coupled to carrier protein.
Formulation	Each vial contains enough antiserum for 500 RIA tubes. The powder should be rehydrated with 50ml RIA buffer. Upon reconstitution to 50ml total volume, the solution contains 0.1M sodium phosphate buffer (pH 7.4), 0.05M NaCl, 0.1% BSA, 0.01% NaN3, and 0.1% Triton X-100. Store at 4°C. This should ensure antibody stability for approximately one month.
Concentration	N/A
Conjugation	Unconjugated
Storage Condition	Original vial: at least one year at 4° - 8°C from date of delivery. Minimize repeated thawing and freezing of the antiserum by freezing aliquots at -20°C or below.
Gene Name	adrenomedullin
Database Link	Entrez Gene 133 Human UniProt ID P35318
Background	Adrenomedullin (ADM or AM) is a vasodilator peptide hormone consisted of 52 amino acids with an intramolecular disulfide bond. It shows a slight homology with the calcitonin gene- related peptide (CGRP). Adrenomedullin was initially isolated from a pheochromocytoma, a tumor of the adrenal medulla. It may function as a hormone in the circulation control because it is found in blood in a considerable concentration. This antibody was generated by immunization of rabbits with Adrenomedullin coupled to a carrier protein.
Synonyms	adrenomedullin; AM; preproadrenomedullin
Reference Data

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