IL21 Receptor (IL21R) Rabbit Polyclonal Antibody

CAT#: TA361162

IL21R Antibody - middle region



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CNY 4,628.00


货期*
2周

规格
    • 50 ug

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经常一起买 (2)
beta Actin Mouse Monoclonal Antibody, Clone OTI1, Loading Control
    • 30 ul

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Transient overexpression lysate of interleukin 21 receptor (IL21R), transcript variant 2
    • 100 ug

CNY 3,080.00

Specifications

Product Data
Applications WB
Reactivity Human
Host Rabbit
Clonality Polyclonal
Immunogen The immunogen is a synthetic peptide directed towards the middle region of human IL21R
Specificity Expected reactivity: Human
Formulation Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Note that this product is shipped as lyophilized powder to China customers.
Concentration lot specific
Purification Affinity purified
Conjugation Unconjugated
Storage Condition For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Predicted Protein Size 59 kDa
Gene Name interleukin 21 receptor
Background The protein encoded by this gene is a cytokine receptor for interleukin 21 (IL21). It belongs to the type I cytokine receptors, and has been shown to form a heterodimeric receptor complex with the common gamma-chain, a receptor subunit also shared by the receptors for interleukin 2, 4, 7, 9, and 15. This receptor transduces the growth promoting signal of IL21, and is important for the proliferation and differentiation of T cells, B cells, and natural killer (NK) cells. The ligand binding of this receptor leads to the activation of multiple downstream signaling molecules, including JAK1, JAK3, STAT1, and STAT3. Knockout studies of a similar gene in mouse suggest a role for this gene in regulating immunoglobulin production. Three alternatively spliced transcript variants have been described.
Synonyms IL-21R; MGC10967; NILR
Reference Data
Protein Families Druggable Genome, Transmembrane
Protein Pathways Cytokine-cytokine receptor interaction, Jak-STAT signaling pathway
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.
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