GABA B Receptor 1 (GABBR1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Reactivity	Human, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen is a synthetic peptide directed towards the C terminal region of human GABBR1
Specificity	Expected reactivity: Human
Formulation	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose. Note that this product is shipped as lyophilized powder to China customers.
Concentration	lot specific
Purification	Affinity purified
Conjugation	Unconjugated
Storage Condition	For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Predicted Protein Size	88 kDa
Gene Name	gamma-aminobutyric acid type B receptor subunit 1
Database Link	NP_001461.1 Entrez Gene 81657 RatEntrez Gene 2550 Human UniProt ID Q59HG8
Background	This gene encodes a receptor for gamma-aminobutyric acid (GABA), which is the main inhibitory neurotransmitter in the mammalian central nervous system. This receptor functions as a heterodimer with GABA(B) receptor 2. Defects in this gene may underlie brain disorders such as schizophrenia and epilepsy. Alternative splicing generates multiple transcript variants, but the full-length nature of some of these variants has not been determined.
Synonyms	dJ271M21.1.1; dJ271M21.1.2; FLJ92613; GABA-B-R1; GABABR1; GABBR1-3; GB1; GPRC3A; hGB1a; OTTHUMP00000109099
Reference Data
Protein Families	Druggable Genome, GPCR, Secreted Protein, Transmembrane
Protein Pathways	Neuroactive ligand-receptor interaction

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