NAALAD2 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen is a synthetic peptide directed towards the middle region of human NAALAD2
Specificity	Expected reactivity: Cow, Dog, Horse, Human, Mouse, Pig, Rabbit, Rat Homology: Cow: 92%; Dog: 100%; Horse: 100%; Human: 100%; Mouse: 100%; Pig: 93%; Rabbit: 79%; Rat: 100%
Formulation	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Predicted Protein Size	31kDa
Gene Name	N-acetylated alpha-linked acidic dipeptidase 2
Database Link	NP_001287859.1 Entrez Gene 10003 Human UniProt ID Q9Y3Q0
Background	This gene is a member of the N-acetylated alpha-linked acidic dipeptidase (NAALADase) gene family. The representative member of this family is the gene encoding human prostate-specific membrane antigen (PSM), which is a marker of prostatic carcinomas and is the first to be shown to possess NAALADase activity. NAALADase cleaves N-acetyl-L-aspartate-L-glutamate (NAAG), which is a neuropeptide expressed both in the central nervous systems and in the periphery and is thought to function as a neurotransmitter. The product of this gene is a type II integral membrane protein. Transient transfection of this gene confers both NAALADase and dipetidyl peptidase IV activities to mammalian cells. This gene is highly expressed in ovary and testis as well as within discrete brain areas. Two transcript variants encoding different isoforms have been found for this gene.
Synonyms	MGC26353; MGC116996; NAADALASE2; NAALADASE2
Reference Data
Protein Families	Druggable Genome, Transmembrane

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