Cacng8 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Reactivity	Mouse
Host	Rabbit
Clonality	Polyclonal
Specificity	Expected reactivity: Cow, Dog, Guinea Pig, Human, Mouse, Pig, Rat Homology: Cow: 100%; Dog: 100%; Guinea Pig: 92%; Human: 100%; Mouse: 100%; Pig: 100%; Rat: 100%
Formulation	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration	lot specific
Purification	Affinity Purified
Conjugation	Unconjugated
Storage Condition	For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Predicted Protein Size	43kDa
Gene Name	calcium channel, voltage-dependent, gamma subunit 8
Database Link	NP_573453 Entrez Gene 81905 Mouse UniProt ID Q8VHW2
Background	Cacng8 regulates the trafficking and gating properties of AMPA-selective glutamate receptors (AMPARs). It promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Cacng8 does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Cacng8 is thought to stabilize the calcium channel in an inactivated (closed) state.
Synonyms	CACNG6
Reference Data

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