IL3RA Rabbit Monoclonal Antibody [Clone ID: DM31]

Specifications

Product Data
Clone Name	DM31
Applications	ELISA, FC
Recommend Dilution	ELISA 1/5000-10000;Flow Cyt  1/100
Reactivity	Human
Host	Rabbit
Clonality	Monoclonal
Immunogen	Recombinant human  CD123(Thr19-Arg305) (TP723926) produced by using human HEK293 cells
Formulation	Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose is added as protectants before lyophilization. Preservative: 0.1% Procline 300
Reconstitution Method	Reconstitute with deionized water
Purification	Purified from cell culture supernatant by affinity chromatography
Conjugation	Unconjugated
Storage Condition	Store at -20°C for 12 months (Avoid repeated freezing and thawing)
Predicted Protein Size	39kDa
Gene Name	interleukin 3 receptor subunit alpha
Database Link	Entrez Gene 3563 Human UniProt ID P26951
Background	Interleukin 3 receptor alpha (low affinity) (IL3RA), also known as CD123 (Cluster of Differentiation 123) is a 70-kD glycoprotein member of the hematopoietin receptor superfamily. This protein associates with a beta subunit common to the receptors for IL-5 and granulocyte-macrophage colony-stimulating factor (GM-CSF) to form a high-affinity receptor for IL-3. The interleukin-3 receptor α chain (CD123) has been identified as a potential immunotherapeutic target because it is overexpressed in AML compared with normal hematopoietic stem cells.
Synonyms	CD123; hIL-3Ra; IL-3R-alpha; IL3R; IL3RAY; IL3RX; IL3RY; MGC34174
Reference Data

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