H2AC20 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB 0.1-1 µg/ml ELISA 0.01-0.1 µg/ml IP 2-5 µg/ml IHC 2-10 µg/ml FC 5-10 µg/ml
Reactivity	Human, Rat, Mouse, Bovine, Chicken, Dog
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthetic peptide derived from C-term of Histone H2A protein.
Formulation	This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.
Purification	The Rabbit IgG is purified by Epitope Affinity Purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	~15 kDa
Gene Name	histone cluster 2, H2ac
Database Link	NP_003508 Entrez Gene 319176 MouseEntrez Gene 499675 RatEntrez Gene 483174 DogEntrez Gene 8338 Human UniProt ID Q16777
Background	Histones are basic nuclear proteins that together with DNA make up the nucleosome structure in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). Histone H1 and the N-terminal tail of H3 have key roles in the folding and inter-association of the chromatin fiber. The llinker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element.
Synonyms	H2A; H2A-GL101; H2AFQ; q
Reference Data
Protein Pathways	Systemic lupus erythematosus

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