PLAC1 Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	WB
Recommend Dilution	WB 0.1-1 µg/ml ELISA 0.01-0.1 µg/ml IP 2-5 µg/ml IHC 2-10 µg/ml FC 5-10 µg/ml
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	A panel of synthetic peptides corresponding to the predicted multiple phosphorylation sites, including S121, Y147, S156. Those sequences are identical to human, rat and mouse.
Formulation	This affinity purified antibody is supplied in sterile Tris-buffered saline (pH7.2) containing antibody stabilizer.
Purification	The Rabbit IgG is purified by Epitope Affinity Purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	~22 kDa
Gene Name	placenta specific 1
Database Link	NP_068568 Entrez Gene 56096 MouseEntrez Gene 317316 RatEntrez Gene 10761 Human UniProt ID Q9HBJ0
Background	The PLAC1, a placenta-specific gene, which encodes a putative cell surface protein, is highly expressed in placenta, testis, cancer cell lines and lung tumors. PLAC1 is exclusively expressed by cells of trophoblastic lineage in the mouse, and maps to a region of the X-chromosome known to be important in placenta growth. PLAC1 is also expressed in human hepatocellular cancer tissues as well as in several other types of cancer tissues and/or tumor cell lines. PLAC1 represents a new class of tumor associated antigen with restricted expression in placenta and cancer tissues, which may serve as a target for cancer vaccination. The phosphorylation of PLAC1 by kinases CDK5, PKC may be involved in tumor associated process.
Synonyms	CT92; OOSP2L
Reference Data
Protein Families	Secreted Protein

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