Fumarylacetoacetate hydrolase (FAH) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB 0.1-1 µg/ml ELISA 0.01-0.1 µg/ml IP 2-5 µg/ml IHC 2-10 µg/ml FC 5-10 µg/ml
Reactivity	Mouse, Human, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	A full length recombinant protein of FAH from mouse origin
Formulation	This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer.
Purification	The Rabbit IgG is purified by Epitope Affinity Purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	~47 kDa
Gene Name	fumarylacetoacetate hydrolase (fumarylacetoacetase)
Database Link	NP_000128 Entrez Gene 14085 MouseEntrez Gene 29383 RatEntrez Gene 2184 Human UniProt ID P16930
Background	Fumarylacetoacetate hydrolase, also known as FAH, is an enzyme that catalyzes the hydrolysis of 4-fumarylacetoacetate into fumarate and acetoacetate. It is the last enzyme in tyrosin catabolism pathway. This enzyme is abundant in the liver and kidney, and smaller amounts are found in many tissues throughout the body. Human genetic disorder hereditary tyrosinemia (HT) is associated with FAH deficiency and liver/ kidney dysfunction.
Synonyms	FLJ51912
Reference Data
Protein Families	Druggable Genome
Protein Pathways	Metabolic pathways, Tyrosine metabolism

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