Ephrin B3 (EFNB3) Rabbit Polyclonal Antibody
CAT#: TA354547
Rabbit anti Ephrin B3 Polyclonal Antibody
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CNY 4,675.00
货期*
5周
规格
经常一起买 (1)
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Specifications
Product Data | |
Applications | IHC, WB |
Recommend Dilution | WB 0.1-1 µg/ml ELISA 0.01-0.1 µg/ml IP 2-5 µg/ml IHC 2-10 µg/ml FC 5-10 µg/ml |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | Recombinant full length (1-340aa) human Ephrin-B34 protein expressed in E.coli. |
Formulation | This affinity purified antibody is supplied in sterile Phosphate buffered saline (pH7.2) containing antibody stabilizer. |
Purification | The Rabbit IgG is purified by Epitope Affinity Purification |
Conjugation | Unconjugated |
Storage Condition | Store at -20°C as received. |
Predicted Protein Size | 35 kDa |
Gene Name | ephrin B3 |
Database Link | |
Background | Ehrin-B3, also known as EFNB3, a member of the ephrin gene family, is important in brain development as well as in its maintenance. It is highly expressed in several forebrain subregions compared to other brain subregions, it may play a pivotal role in forebrain function. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. The ephrin ligands and receptors have been divided into two major subclasses: Ephrin-A and ephrin-B. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. The Eph family of receptors are similarly divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. |
Synonyms | EFL6; EPLG8; LERK8 |
Reference Data | |
Protein Families | Druggable Genome, Transmembrane |
Protein Pathways | Axon guidance |
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